Endocrine Abstracts

Introduction: Parathyroid adenoma is the most common cause of primary hyperparathyroidism (PHPT) resulting in hypercalcemia and hypercalciuria due to autonomous secretion of PTH. Ectopic parathyroid adenoma, as a consequence of variability in the glandular tissue migration during the embryologic life or a supernumary fifth parathyroid gland, has an incidence of 25% among patients with PHPT. The incidence of deeply mediastinal ectopic parathyroid adenoma is 1–3%.<p cla...

Introduction: Gonadotrophin-producing pituitary adenomas are usually non-functioning masses, and are not associated with elevated serum gonadotrophins. Functioning LH-producing gonadotroph pituitary adenomas are exceedingly rare in males, causing elevation of serum testosterone.Case report: We present an adult male who has been admitted to the emergency department a comatose state. Brain MRI revealed a large, lobulated mass of 6 cm caudal and 7.8 cm late...

Introduction: Prolactinomas are rarely found in adolescents under 15 (incidence 0.1/1.000.000). They account for 50% of all types of pituitary adenomas in childhood and adolescence (2% of intracranial tumors). The mean time from onset of symptoms to diagnosis is 2.4 years on average for girls. In cases of macroadenomas, TSH and GH deficiency may coexist. The gold standard primary therapy is dopamine agonists. In case of non-response, or the presence of large prolactinomas with...